Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dichloromethane → 4-(4-Chlorobenzoyl)-piperazin-1-yl-acetic acid morpholide hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dichloromethane | HCID 6344 | — |
| 반응물 | 2-Chlorobenzoyl chloride | HCID 69110 | — |
| 반응물 | 1-(Morpholinocarbonylmethyl)piperazine | HCID 100622 | — |
| 생성물 | 4-(4-Chlorobenzoyl)-piperazin-1-yl-acetic acid morpholide hydrochloride | HCID 86740986 | — |
반응 단계
5 g of piperazinoacetic acid morpholide and 4.2 g of chlorobenzoyl chloride are brought together in 50 ml of methylene chloride at 0° C. The mixture is stirred at room temperature for 2 hours and cooled again to 0° C., whereupon a precipitate separates out, and is recrystallised from isopropanol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04610984 |
| 출처 데이터셋 | uspto-grants-1986_09 |
| ORD ID | ord-00c9c449b98d467ca6ce6714565bfd2c |
| 출처 메모 | uspto-grants-1986_09 |