Acetic acid, 2-(4-nitrophenyl)hydrazide → Acetic acid, 2-(4-aminophenyl)hydrazide

HRID 648900노트

반응식

HRID 648900 반응식
[C:1]([NH:4][NH:5][C:6]1[CH:11]=[CH:10][C:9]([N+:12]([O-])=O)=[CH:8][CH:7]=1)(=[O:3])[CH3:2]>C(O)C.[C].[Pd]>[C:1]([NH:4][NH:5][C:6]1[CH:11]=[CH:10][C:9]([NH2:12])=[CH:8][CH:7]=1)(=[O:3])[CH3:2]

참가 물질

4

반응물 1

HCID 3404344Acetic acid, 2-(4-nitrophenyl)hydrazide

생성물 1

HCID 81068Acetic acid, 2-(4-aminophenyl)hydrazide수율 75%

시약·촉매·용매 2

HCID 178418390HCID 178418390, 화합물촉매HCID 702Ethanol용매

실험 절차

Then, 16.6 g of 1-acetyl-2-(4-nitrophenyl)hydrazine was catalytically reduced in 800 ml of ethanol at room temperature using palladium-carbon as a catalyst. The reaction mixture was filtered and cooled to provide 10.5 g of 1-acetyl-2-(4-aminophenyl)hydrazine. The yield was 75% and the melting point was 130°-140° C.

후처리

  1. filtrationThe reaction mixture was filtered
  2. temperaturecooled

출처 및 근거

ORD 기록
ord-f2ee15792c1e416587b532ef13c46798
출처 데이터셋
uspto-grants-1988_04
특허 번호
US04737452

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