Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Iodopropane → 3-Methoxy-2-methyl-4-propoxypyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Iodopropane | HCID 33643 | — |
| 반응물 | 3-Methoxy-2-methyl-1H-pyridin-4-one | HCID 323424 | — |
| 촉매 | Silver(II) oxide | HCID 92152 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 3-Methoxy-2-methyl-4-propoxypyridine | HCID 13982948 | — |
반응 단계
3-Methoxy-2-methyl-4(1H)-pyridone(1.39 g) and propyl iodide (2.0 ml) were dissolved in dimethylformamide (20 ml), to which silver oxide (2.31 g) was added in small portions and stirred vigorously at room temperature for 5 hours. The reaction mixture was diluted with chloroform (100 ml), washed with water, dried and evaporated. The residue was purified by flash chromatography (chloroform) on silica gel, to give 3-methoxy-2-methyl-4-propoxypyridine (1.7 g) as a light brown oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04738975 |
| 출처 데이터셋 | uspto-grants-1988_04 |
| ORD ID | ord-2a493dc1dce0447e91aa00ee831790d4 |
| 출처 메모 | uspto-grants-1988_04 |