m-Chloroperbenzoic acid → 2-Oxiranylmethoxyphenylsulfonamide
반응식
ClC1C=CC=C(C(OO)=[O:9])C=1.[CH2:12]([O:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[S:22]([NH2:25])(=[O:24])=[O:23])[CH:13]=[CH2:14]>C(Cl)Cl>[O:9]1[CH2:14][CH:13]1[CH2:12][O:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[S:22]([NH2:25])(=[O:23])=[O:24]참가 물질
4
실험 절차
To a mixture of 15.3 g of 3-chloroperbenzoic acid in 270 ml of absolute methylene chloride are added 14.2 g of 2-allyloxyphenylsulfonamide over 2 minutes. The solution is then heated to reflux for 3 hours, cooled, and then washed three times with saturated sodium carbonate solution and once with water. The organic phase is dried and concentrated, affording 11.9 g of 2-oxiranylmethoxyphenylsulfonamide with a melting point of 132°-133° C.
후처리
- temperatureThe solution is then heated
- temperatureto reflux for 3 hours
- temperaturecooled
- washwashed three times with saturated sodium carbonate solution
- customThe organic phase is dried
- concentrationconcentrated
출처 및 근거
- ORD 기록
- ord-2b3febd65829459aa2bbb433a94be3fa
- 출처 데이터셋
- uspto-grants-1988_04
- 특허 번호
- US04739068
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