Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → Phosphoramidic dichloride, bis(2-chloroethyl)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Bis(2-chloroethyl)amine | HCID 9533 | — |
| 반응물 | Triethylamine hydrochloride | HCID 11130 | — |
| 반응물 | Phosphorus oxychloride | HCID 24813 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | Phosphoramidic dichloride, bis(2-chloroethyl)- | HCID 96271 | — |
반응 단계
Phosphorous oxychloride (0.15 mol) in 100 ml. THF are mixed dropwise at 10° C. with bis-chloroethylamine (0.1 mol) in 100 ml. THF and triethylamine (0.15 mol). After ending of the reaction (TLC verification), triethylamine hydrochloride is filtered off and the filtrate, after the addition of 50 ml. toluene, evaporated. The oily residue is immediately further reacted.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04739095 |
| 출처 데이터셋 | uspto-grants-1988_04 |
| ORD ID | ord-c0af85cf54a442ee855b99cb32b2c48a |
| 출처 메모 | uspto-grants-1988_04 |