Ammonia → 2-Cyano-2-phenylacetamide
반응식
[C:1]([CH:3]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:4](OC)=[O:5])#[N:2].[NH3:14]>C1C=CC=CC=1>[C:1]([CH:3]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:4]([NH2:14])=[O:5])#[N:2]참가 물질
4
실험 절차
A 10% solution of methyl 2-cyano-2-phenylacetate in benzene is saturated with ammonia under ice cooling. The reaction mixture is allowed to stand at room temperature for 2 hours, and then the product is filtered off. 2-Cyano-2-phenylacetic acid amide is obtained with a yield of 75%; m.p.: 148.5°-150° C.
후처리
- filtrationthe product is filtered off
출처 및 근거
- ORD 기록
- ord-fbe203fd70f64ea5ae552f9b04e0a270
- 출처 데이터셋
- uspto-grants-1988_04
- 특허 번호
- US04740228
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