Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 649499생성일: 2026년 10월 26일
4,5-Dihydro-2-(methylthio)thiazole → 3-[2-(2,5-Diketopyrrolidyl)ethyl]-2-methylthiothiazolinium bromide
https://huagongshe.com/reaction/649499
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 4,5-Dihydro-2-(methylthio)thiazole | HCID 88324 | — |
| 반응물 | 2-(2,5-Diketopyrrolidyl)ethyl bromide | HCID 178515929 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 3-[2-(2,5-Diketopyrrolidyl)ethyl]-2-methylthiothiazolinium bromide | HCID 178503408 | 66% |
반응 단계
6.6 g (5×10-2 mols) of 2-methylthiothiazoline and 12.0 g (6×10-2 mols) of 2-(2,5-diketopyrrolidyl)ethyl bromide were heated with stirring for about 3 hours on an oil bath which had been heated to a temperature of 130° C. Thereafter, the reaction system was allowed to cool to room temperature. 50 ml of acetone was added to the reaction system. The resulting precipitate was recovered by decantation. 11.1 g of the desired product was obtained in a 66% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04740455 |
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| 출처 데이터셋 | uspto-grants-1988_04 |
|---|
| ORD ID | ord-9a83121b071b42cc95706ec848098b96 |
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| 출처 메모 | uspto-grants-1988_04 |
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