Succinyl chloride → N,N'-Bis-((R)-1-indanyl)succinamide

반응식

[NH2:1][C@H:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3]1.[C:11](Cl)(=[O:17])[CH2:12][CH2:13][C:14](Cl)=[O:15]>>[C@H:2]1([NH:1][C:11](=[O:17])[CH2:12][CH2:13][C:14]([NH:1][C@H:2]2[C:10]3[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=3)[CH2:4][CH2:3]2)=[O:15])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3]1

참가 물질

반응물 2

HCID 10970Succinyl chloride

HCID 2733933(R)-(-)-1-Aminoindan

생성물 1

HCID 53712777N,N'-Bis-((R)-1-indanyl)succinamide

실험 절차

This was prepared by the same procedure as in Example 73 starting from (R)-1-aminoindan (8.02 g, 60 mmole) and succinoyl chloride (2.32 g, 14 mmole), to give the white product, (1.30 g, 26.70%). Melting point: 266-9° C.

후처리

customto give the white product, (1.30 g, 26.70%)

출처 및 근거

ORD 기록: ord-4ec4db2ac54d4b8f94536b12853aa321
출처 데이터셋: uspto-grants-2001_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06271263B1

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