Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isobutylene oxide → 4-Aza-4-butyl-2,2-dimethyl-1-oxaspiro[4.5]decane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isobutylene oxide | HCID 11208 | — |
| 반응물 | N-cyclohexylidenebutylamine | HCID 19875469 | — |
| 반응물 | HCID 178506586 | HCID 178506586 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 4-Aza-4-butyl-2,2-dimethyl-1-oxaspiro[4.5]decane | HCID 21714731 | 85% |
반응 단계
A mixture of 1 mmol of N-cyclohexylidenebutylamine, 2 mmol of 1,2-epoxy-2-methylpropane, 0.05 mmol of samarium(II) iodide (SmI2), and 1 ml of tetrahydrofuran was stirred at room temperature for 5 hours. Products in the reaction mixture was isolated through column chromatography to yield 4-aza-4-butyl-2,2-dimethyl-1-oxaspiro[4.5]decane of the following formula in yield of 85%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06271387B1 |
| 출처 데이터셋 | uspto-grants-2001_08 |
| ORD ID | ord-7d0f853d06584fc1b3a914b49da0af2d |
| 출처 메모 | uspto-grants-2001_08 |