1,3-Benzodioxole-5-carboxylic acid → 1,3-Benzodioxole-5-carbonyl chloride

반응식

[C:1]([OH:12])(=O)[C:2]1[CH:10]=[CH:9][C:8]2[O:7][CH2:6][O:5][C:4]=2[CH:3]=1.S(Cl)([Cl:15])=O>>[C:1]([Cl:15])(=[O:12])[C:2]1[CH:10]=[CH:9][C:8]2[O:7][CH2:6][O:5][C:4]=2[CH:3]=1

참가 물질

반응물 2

HCID 71961,3-Benzodioxole-5-carboxylic acid

HCID 24386Thionyl Chloride

생성물 1

HCID 27347491,3-Benzodioxole-5-carbonyl chloride

실험 절차

In 6 ml of thionyl chloride was suspended 5.0 g of piperonylic acid. The suspension was refluxed for 8 hours. Excess volume of thionyl chloride was evaporated off under reduced pressure to give crude crystals of piperonylic acid chloride.

후처리

temperatureThe suspension was refluxed for 8 hours
customExcess volume of thionyl chloride was evaporated off under reduced pressure

출처 및 근거

ORD 기록: ord-1d11c5876e414d0185f4cd42bc97df70
출처 데이터셋: uspto-grants-1986_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04612321

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