2-(4,4-Difluorobut-3-enylthio)benzthiazole → HCID 21712906, 화합물

HRID 650616

반응식

HRID 650616 반응식
[F:1][C:2]([F:16])=[CH:3][CH2:4][CH2:5][S:6][C:7]1[S:8][C:9]2[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=2[N:11]=1.[OH2:17].[OH2:18].O.O.O.O.C(OO)(=O)C1C(=CC=CC=1)C(O)=O.[Mg]>ClCCl.O>[F:16][C:2]([F:1])=[CH:3][CH2:4][CH2:5][S:6]([C:7]1[S:8][C:9]2[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=2[N:11]=1)(=[O:18])=[O:17]

참가 물질

5

반응물 2

HCID 217129092-(4,4-Difluorobut-3-enylthio)benzthiazoleHCID 86597096Magnesium monoperoxyphthalic acid hexahydrate

생성물 1

HCID 21712906HCID 21712906, 화합물

시약·촉매·용매 2

HCID 962Water용매2회HCID 6344Dichloromethane용매2회

실험 절차

2-(4,4-difluorobut-3-enylthio)benzthiazole (prepared by the method described in United Kingdom Patent Application GB2270689A, 8.25 g) in dichloromethane ( 15 cm3) was added to a rapidly stirred mixture of monomagnesium peroxyphthalic acid hexahydrate (25.7 g, 70-80% technical grade) in water (25 cm3). The mixture was stirred for 2 days, diluted with dichloromethane and water, the organic phase separated, washed with aqueous sodium carbonate, water and dried (magnesium sulfate). The solvent was evaporated under reduced pressure to give 2-(4,4-difluorobut-3-enylsulfonyl )benzthiazole as a colourless oil, 4.9 g.

후처리

  1. customthe organic phase separated
  2. washwashed with aqueous sodium carbonate, water
  3. dry with materialdried (magnesium sulfate)
  4. customThe solvent was evaporated under reduced pressure

출처 및 근거

ORD 기록
ord-239314f354524ad9b811097d7640845e
출처 데이터셋
uspto-grants-2001_08
특허 번호
US06274632B1

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