Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
7-Oxodehydroepiandrosterone 3-acetate → 7-Keto-dehydroepiandrosterone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 7-Oxodehydroepiandrosterone 3-acetate | HCID 9798229 | — |
| 용매 | Acetone hexane | HCID 21880519 | — |
| 생성물 | 7-Keto-dehydroepiandrosterone | HCID 193313 | — |
반응 단계
The last remains of the product (3) from the mother liquor were obtained by column chromatography of the mother liquor (adsorbed on silica gel) on a small column of silica gel (80-200 mesh) utilizing hexane-acetone (85:15) as eluent. An additional 0.15 gm of 7-oxo-DHEA-Ac (3) was obtained. Total yield 1.75 gm, 56.5% (based on 90% conversion), melting point 185-186° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06274746B1 |
| 출처 데이터셋 | uspto-grants-2001_08 |
| ORD ID | ord-0d502652bd5e4f399ebf5446d026786f |
| 출처 메모 | uspto-grants-2001_08 |