HCID 13714726, 화합물 → HCID 13714728, 화합물

HRID 65094노트

반응식

HRID 65094 반응식
[CH:1]([C:4]([C:24]1[CH:29]=[C:28]([O:30][CH3:31])[C:27]([O:32][CH3:33])=[C:26]([O:34][CH3:35])[CH:25]=1)([CH2:7][CH2:8][CH2:9][NH:10][CH2:11][CH2:12][CH2:13][O:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[N+:21]([O-])=O)[C:5]#[N:6])([CH3:3])[CH3:2]>CO.[Pt]=O>[CH:1]([C:4]([C:24]1[CH:29]=[C:28]([O:30][CH3:31])[C:27]([O:32][CH3:33])=[C:26]([O:34][CH3:35])[CH:25]=1)([CH2:7][CH2:8][CH2:9][NH:10][CH2:11][CH2:12][CH2:13][O:14][C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[NH2:21])[C:5]#[N:6])([CH3:3])[CH3:2]

참가 물질

4

반응물 1

HCID 13714726HCID 13714726, 화합물

생성물 1

HCID 13714728HCID 13714728, 화합물수율 97.2%

시약·촉매·용매 2

HCID 82844Platinum oxide (PtO)촉매HCID 887Methanol용매

실험 절차

4.78 g of alpha-isopropyl-alpha-[3-[N-[3-(2-nitrophenoxy)propyl]amino]propyl]-3,4,5-trimethoxyphenyl-acetonitrile was hydrogenated in 100 ml of methanol over 50 mg of platinum oxide at atmospheric pressure and room temperature. The catalyst was filtered off and filtrate was evaporated to give 4.36 g of desired compound as a pale yellow oil.

후처리

  1. filtrationThe catalyst was filtered off
  2. customfiltrate was evaporated

출처 및 근거

ORD 기록
ord-0def383bcd52460d8c89ff77202dcd60
출처 데이터셋
uspto-grants-1986_09
특허 번호
US04612329

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