HCID 13714730, 화합물 → HCID 13714732, 화합물

HRID 65097노트

반응식

HRID 65097 반응식
[CH:1]([C:4]([C:25]1[CH:30]=[C:29]([O:31][CH3:32])[C:28]([O:33][CH3:34])=[C:27]([O:35][CH3:36])[CH:26]=1)([CH2:7][CH2:8][CH2:9][N:10]([CH2:12][CH2:13][CH2:14][O:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[N+:22]([O-])=O)[CH3:11])[C:5]#[N:6])([CH3:3])[CH3:2]>CO.[Pt]=O>[CH:1]([C:4]([C:25]1[CH:30]=[C:29]([O:31][CH3:32])[C:28]([O:33][CH3:34])=[C:27]([O:35][CH3:36])[CH:26]=1)([CH2:7][CH2:8][CH2:9][N:10]([CH2:12][CH2:13][CH2:14][O:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=1[NH2:22])[CH3:11])[C:5]#[N:6])([CH3:3])[CH3:2]

참가 물질

4

반응물 1

HCID 13714730HCID 13714730, 화합물

생성물 1

HCID 13714732HCID 13714732, 화합물수율 105.2%

시약·촉매·용매 2

HCID 82844Platinum oxide (PtO)촉매HCID 887Methanol용매

실험 절차

0.92 g of alpha-isopropyl-alpha-[3-[N-[3-(2-nitrophenoxy)propyl]-N-methylamino]propyl]-3,4,5-trimethoxyphenylacetonitrile was hydrogenated in 20 ml of methanol over 10 mg of platinum oxide at atmospheric pressure and room temperature. The catalyst was filtered off and filtrate was evaporated to give 0.91 g of the desired compound as a yellow oil. The oxalate of this compound was obtained in the usual manner.

후처리

  1. filtrationThe catalyst was filtered off
  2. customfiltrate was evaporated

출처 및 근거

ORD 기록
ord-2f0e8264333b4780b3d6f70d45b41568
출처 데이터셋
uspto-grants-1986_09
특허 번호
US04612329

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