Methanesulfonyl chloride → N-[6-chloro-2-(3-methylbenzoyl)-1H-indol-3-yl]methanesulfonamide

HRID 651025

반응식

HRID 651025 반응식
[NH2:1][C:2]1[C:10]2[C:5](=[CH:6][C:7]([Cl:11])=[CH:8][CH:9]=2)[N:4](C(OCC)=O)[C:3]=1[C:17](=[O:25])[C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH3:24])[CH:19]=1.[CH3:26][S:27](Cl)(=[O:29])=[O:28]>>[Cl:11][C:7]1[CH:6]=[C:5]2[C:10]([C:2]([NH:1][S:27]([CH3:26])(=[O:29])=[O:28])=[C:3]([C:17](=[O:25])[C:18]3[CH:23]=[CH:22][CH:21]=[C:20]([CH3:24])[CH:19]=3)[NH:4]2)=[CH:9][CH:8]=1

참가 물질

3

반응물 2

HCID 31297Methanesulfonyl chlorideHCID 183680433-Amino-6-chloro-2-(3-methylbenzoyl)-1-(ethoxycarbonyl)indole

생성물 1

HCID 9928948N-[6-chloro-2-(3-methylbenzoyl)-1H-indol-3-yl]methanesulfonamide

실험 절차

The title compound was prepared according to the procedure described in Example 33 from ethyl 3-amino-6-chloro-2-(3-methylbenzoyl)-1H-indole-1-carboxylate (step 1 of Example 3) and methanesulfonyl chloride.

출처 및 근거

ORD 기록
ord-05c6ac11646a41e2a4f9ffd47fbe163f
출처 데이터셋
uspto-grants-2001_08
특허 번호
US06277878B1

연결된 노트

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