Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methylamine hydrochloride → (S)-(1-Methylcarbamoyl-2-thiazol-4-yl-ethyl)-carbamic acid tert-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methylamine hydrochloride | HCID 6364545 | — |
| 반응물 | 2-((tert-Butoxycarbonyl)amino)-3-(thiazol-4-yl)propanoic acid | HCID 14540322 | — |
| 생성물 | (S)-(1-Methylcarbamoyl-2-thiazol-4-yl-ethyl)-carbamic acid tert-butyl ester | HCID 22850398 | — |
반응 단계
Methylamine hydrochloride (1.2 mmol) and Boc-L-3-(4-thiazolyl)alanine (1.0 mmol) were coupled according to Procedure A (0-25° C. reaction temperature, acid wash omitted) and the product used without further purification. Yield, 250 mg, 88%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06277877B1 |
| 출처 데이터셋 | uspto-grants-2001_08 |
| ORD ID | ord-0991791ec76a4a95a874a3d3b169645c |
| 출처 메모 | uspto-grants-2001_08 |