Water → HCID 178525532, 화합물

HRID 65122

반응식

HRID 65122 반응식
S[C:2]1[S:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[C:11]1(=[O:17])[O:16][C:14](=[O:15])[CH:13]=[CH:12]1.O.[S:19](=O)(=O)(O)O>>[S:3]1[C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=[C:2]1[CH:12]([CH2:13][C:14]([OH:16])=[O:15])[C:11]([OH:17])=[S:19]

참가 물질

5

반응물 4

HCID 962WaterHCID 1118Sulfuric AcidHCID 7923Maleic AnhydrideHCID 178418395HCID 178418395, 화합물

생성물 1

HCID 178525532HCID 178525532, 화합물수율 87%

실험 절차

16.8 g of finely powdered 2-mercaptobenzothiazole are suspended in 40 ml of 70% sulfuric acid, and 10.2 g of powdered maleic anhydride are added at 48°-51° in the course of 1 hour, with stirring. After a further hour at 50°, the reaction mixture is cooled to room temperature and is diluted by dropwise addition of 250 ml of water at 25°-35°. After 1 hour, the precipitated product is filtered off and dissolved in dilute sodium hydroxide solution. The solution is filtered and the filtrate is acidified with hydrochloric acid. The precipitate is filtered off and dried at 60° in vacuo. 24.7 g (87% of theory) of benzothiazol-2-ylthiosuccinic acid of melting point 175°-176°, with decomposition, are thus obtained.

후처리

  1. waitAfter a further hour at 50°
  2. filtrationthe precipitated product is filtered off
  3. dissolutiondissolved in dilute sodium hydroxide solution
  4. filtrationThe solution is filtered
  5. filtrationThe precipitate is filtered off
  6. customdried at 60° in vacuo

출처 및 근거

ORD 기록
ord-aa7ce148d31c4b488ae35901f579ecc8
출처 데이터셋
uspto-grants-1986_09
특허 번호
US04612378

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