참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ethyl Acetate | HCID 8857 | — |
| 반응물 | Methylurea | HCID 11719 | — |
| 반응물 | Ethyl 3,4-dimethoxybenzoylacetate | HCID 2758465 | — |
| 용매 | Tetralin | HCID 8404 | — |
| 생성물 | 6-(3,4-dimethoxyphenyl)-3-methyl-2,4(1H,3H)-pyrimidinedione | HCID 13714258 | 40.3% |
반응 단계
To a solution of ethyl veratroylacetate (8.0 g) in tetralin (24 ml) was added N-methylurea (3.52 g) and the mixture was heated for an hour at 170° C. After being cooled to 95° C., ethyl acetate (33 ml) was added thereto. The precipitate was collected by filtration and washed with ethyl acetate to give 6-(3,4-dimethoxyphenyl)-3-methyl-2,4(1H,3H)-pyrimidinedione (3.35 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04612376 |
|---|
| 출처 데이터셋 | uspto-grants-1986_09 |
|---|
| ORD ID | ord-ac4b51625d934dca87d4af4f9d803b3c |
|---|
| 출처 메모 | uspto-grants-1986_09 |
|---|
