Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Mandelic Acid → Sotalol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Mandelic Acid | HCID 1292 | — |
| 반응물 | Dexsotalol Hydrochloride | HCID 165245 | — |
| 생성물 | Sotalol | HCID 5253 | — |
반응 단계
In addition, using chemical method as described by Le Garrec (1987), enriched d-sotalol hydrochloride and l-sotalol hydrochloride were prepared using mandelic acid and subjected to conversion to the base form, chiral separation and reconversion to hydrochloride salt was carried out. The details of these procedures are given below:
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06281246B1 |
| 출처 데이터셋 | uspto-grants-2001_08 |
| ORD ID | ord-b1da450602074d29b7a1aa7f0ca08711 |
| 출처 메모 | uspto-grants-2001_08 |