Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethylene Glycol → 2-(2-((Tert-butyldimethylsilyl)oxy)ethoxy)ethanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethylene Glycol | HCID 8117 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | Tert-butyldimethylsilane chloride | HCID 131722836 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-(2-((Tert-butyldimethylsilyl)oxy)ethoxy)ethanol | HCID 11117582 | 97.9% |
반응 단계
20 g of diethyleneglycol is added to 9.05 g of sodium hydride in 320 cm3 of tetrahydrofuran, the reaction medium is agitated for 45 minutes, 28.3 g of dimethylterbutylsilane chloride is added, agitation is carried out for 3 hours while leaving the temperature to return to ambient. Extraction is carried out with ether, followed by washing with an aqueous solution of sodium bicarbonate, with salt water, drying and evaporating the solvent. 40.25 g of expected product is obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06281204B1 |
| 출처 데이터셋 | uspto-grants-2001_08 |
| ORD ID | ord-ea06e4a76b824325b25c383d0b6d803b |
| 출처 메모 | uspto-grants-2001_08 |