참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Methyl chloroglyoxylate | HCID 79846 | — |
| 반응물 | 6-methoxy-1-methyl-1H-indole | HCID 4777929 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | methyl (6-methoxy-1-methyl-1H-indol-3-yl)glyoxylate | HCID 84741837 | 41% |
반응 단계
6-Methoxy-1-methyl-1H-indole (1.0 g, 6.19 mmol) was dissolved in ether (10 mL) and cooled to 0° C. Methyl chlorooxoacetate (1.17 mL, 12.4 mmol) was added dropwise. Stirring was continued at 0° C. for 6 h. The mixture was filtered and washed well with ether to give methyl (6-methoxy-1-methyl-1H-indol-3-yl)glyoxylate (621 mg, 41%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06281356B1 |
|---|
| 출처 데이터셋 | uspto-grants-2001_08 |
|---|
| ORD ID | ord-ed957cc20c3948879785331dc05d89d3 |
|---|
| 출처 메모 | uspto-grants-2001_08 |
|---|
