Acetic Acid → HCID 13687205, 화합물

HRID 651904노트

반응식

HRID 651904 반응식
[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([NH:11][NH2:12])=[C:4]([F:13])[CH:3]=1.[C:14]([CH:17]1[CH2:22][CH2:21][CH2:20][CH2:19][C:18]1=O)(=O)[CH3:15].C(O)(=O)C>C1(C)C(C)=CC=CC=1>[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([N:11]2[C:14]([CH3:15])=[C:17]3[C:18]([CH2:19][CH2:20][CH2:21][CH2:22]3)=[N:12]2)=[C:4]([F:13])[CH:3]=1

참가 물질

5

반응물 3

HCID 176Acetic AcidHCID 134002-AcetylcyclohexanoneHCID 13629447HCID 13629447, 화합물

생성물 1

HCID 13687205HCID 13687205, 화합물수율 38.2%

시약·촉매·용매 1

HCID 7237O-Xylene용매

실험 절차

In the same manner as in Example 6 but using 4-chloro-2-fluoro-5-nitrophenylhydrazine (4 g), 2-acetylcyclohexanone (2.8 g), a catalytic amount of acetic acid and xylene (10 ml), there was produced 2.3 g of 2-(4-chloro-2-fluoro-5-nitrophenyl)-3-methyl-4,5,6,7-tetrahydro-2H-indazole. m.p., 143°-144° C.

출처 및 근거

ORD 기록
ord-08cca122c43a45a6957e269e356d12a7
출처 데이터셋
uspto-grants-1987_06
특허 번호
US04670043

반응 노트

불러오는 중…