Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cholesterol → 1,4,6-Cholestatrien-3-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cholesterol | HCID 5997 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 1,4,6-Cholestatrien-3-one | HCID 107390 | 60.5% |
반응 단계
Cholesterol (19.3 gms) and dichlorodicyanoquinone (38 gms) in dry dioxan (500 ml) were heated under reflux for 22 hrs. The mixture was then cooled, filtered and the filtrate evaporated to dryness. Chromatography of the residue on alumina and elution with benzene/hexane followed by elution with benzene afforded the trienone as a pale oil (11.5 gms) which solidified on standing. Physical properties of this material were appropriate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04670190 |
| 출처 데이터셋 | uspto-grants-1987_06 |
| ORD ID | ord-b8b7c550be1944b7b8496543f44a2355 |
| 출처 메모 | uspto-grants-1987_06 |