Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
25-Hydroxycholesterol → 25-Hydroxycholesta-1,4,6-trien-3-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 25-Hydroxycholesterol | HCID 65094 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 25-Hydroxycholesta-1,4,6-trien-3-one | HCID 22797387 | — |
반응 단계
25-Hydroxycholesterol (3.4 gms) and dichlorodicyanoquinone (6.5 gms) dissolved in purified dioxan (100 mls) were heated at reflux for 20 hrs. The mixture was filtered and the solvent evaporated. Chromatography of the residue on alumina and elution with ethyl acetate and benzene afforded the trienone. Recrystallization from methanol gave the title compound, melting point 183°-184°. νmax. 3600, 1650 and 1600 cm-1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04670190 |
| 출처 데이터셋 | uspto-grants-1987_06 |
| ORD ID | ord-3c2068ef9cc742e1ade3feaa90bafb20 |
| 출처 메모 | uspto-grants-1987_06 |