Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dichloromethane → 1-(Methoxycarbonyl)propyl 4-[14-(trimethylsilyl)tetradecylamino]benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dichloromethane | HCID 6344 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Methyl 2-hydroxybutanoate | HCID 520445 | — |
| 반응물 | 4-[14-(Trimethylsilyl)tetradecylamino]benzoyl chloride hydrochloride | HCID 20198230 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 1-(Methoxycarbonyl)propyl 4-[14-(trimethylsilyl)tetradecylamino]benzoate | HCID 20198267 | — |
반응 단계
To a solution of 10.0 g. 4-[14-(trimethylsilyl)tetradecylamino]benzoyl chloride hydrochloride in 200 ml. methylene chloride is added dropwise a solution of 3 g. methyl α-hydroxybutyrate and 5 g. triethylamine in 100 ml. ether. After 17 hours stirring at room temperature, the precipitate is collected and washed with several portions of ether. The ether solution is washed with water, dried and evaporated to yield the product as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04670421 |
| 출처 데이터셋 | uspto-grants-1987_06 |
| ORD ID | ord-703c8991bd5548c08ffbd47fb47e00ab |
| 출처 메모 | uspto-grants-1987_06 |