Triethylamine → 2-Nonyn-1-ol methanesulfonate

HRID 652112노트

반응식

HRID 652112 반응식
[CH2:1]([OH:10])[C:2]#[C:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9].C(N(CC)CC)C.[CH3:18][S:19](Cl)(=[O:21])=[O:20]>C(Cl)Cl>[CH3:18][S:19]([O:10][CH2:1][C:2]#[C:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9])(=[O:21])=[O:20]

참가 물질

5

반응물 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 80017Non-2-yn-1-ol

생성물 1

HCID 138851622-Nonyn-1-ol methanesulfonate

시약·촉매·용매 1

HCID 6344Dichloromethane용매2회

실험 절차

To a cooled (0° C.) solution of 14.6 g (0.104 mole) of 2-nonyn-1-ol in 150 ml of dry methylene chloride and 23.14 ml (0.166 mole) of triethylamine there were added dropwise 10.7 ml (0.156 mole) of methanesulfonyl chloride. The reaction mixture was stirred for 30 minutes at the same temperature, diluted with methylene chloride (150 ml), washed with brine (100 ml), dried and evaporated under vacuum to provide 2-nonyn-1-ol methanesulfonate.

후처리

  1. washwashed with brine (100 ml)
  2. customdried
  3. customevaporated under vacuum

출처 및 근거

ORD 기록
ord-ceb16bc8b5cf4dbc9a8210c6f52a4bcd
출처 데이터셋
uspto-grants-1987_06
특허 번호
US04670465

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