2-Acetylnaphthalene → 2,2-Dihydroxy-1-(naphthalen-2-yl)ethanone
반응식
C([C:4]1[CH:13]=[CH:12][C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=1)(=O)C.[Se](=O)=[O:15].[O:17]1[CH2:22][CH2:21][O:20]CC1>O>[OH:15][CH:21]([OH:20])[C:22]([C:9]1[CH:8]=[CH:7][C:6]2[C:11](=[CH:12][CH:13]=[CH:4][CH:5]=2)[CH:10]=1)=[O:17]참가 물질
5
실험 절차
A mixture of 45.1 g of 2'-acetonaphthone, 29.4 g of selenium dioxide, 350 ml of dioxane and 7.0 ml of water was stirred, heated carefully to reflux and maintained at reflux for 3 hours. The mixture was cooled, filtered through diatomaceous earth and the filtrate evaporated in vacuo. The residue was treated with 300 ml of water and the resulting white solid collected and recrystallized from aqueous acetone giving the desired product as white crystals, mp 103°-120° C.
후처리
- temperatureheated carefully
- temperatureto reflux
- temperaturemaintained
- temperatureat reflux for 3 hours
- temperatureThe mixture was cooled
- filtrationfiltered through diatomaceous earth
- customthe filtrate evaporated in vacuo
- additionThe residue was treated with 300 ml of water
- customthe resulting white solid collected
- customrecrystallized from aqueous acetone giving the desired product as white crystals, mp 103°-120° C.
출처 및 근거
- ORD 기록
- ord-bd67e94d858a409e93036f961ee4abdc
- 출처 데이터셋
- uspto-grants-1986_09
- 특허 번호
- US04613611
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