Pyridine, 3-(4-aminobutyl)- → HCID 20197288, 화합물
반응식
[C:1]([C:4]1[CH:23]=[CH:22][C:7]([O:8][CH2:9][C:10]2[C:11]([O:19][CH2:20][CH3:21])=[C:12]([CH:16]=[CH:17][CH:18]=2)[C:13](O)=[O:14])=[C:6]([CH2:24][CH2:25][CH3:26])[C:5]=1[OH:27])(=[O:3])[CH3:2].[N:28]1[CH:33]=[CH:32][CH:31]=[C:30]([CH2:34][CH2:35][CH2:36][CH2:37]N)[CH:29]=1.C(C1C=CC(OCC2C=CC(C([NH2:54])=O)=C(OCC)C=2CCCCC2C=NC=CC=2)=C(CCC)C=1O)(=O)C>>[C:1]([C:4]1[CH:23]=[CH:22][C:7]([O:8][CH2:9][C:10]2[C:11]([O:19][CH2:20][CH3:21])=[C:12]([CH:16]=[CH:17][C:18]=2[CH2:37][CH2:36][CH2:35][CH2:34][C:30]2[CH:29]=[N:28][CH:33]=[CH:32][CH:31]=2)[C:13]([NH2:54])=[O:14])=[C:6]([CH2:24][CH2:25][CH3:26])[C:5]=1[OH:27])(=[O:3])[CH3:2]참가 물질
4
실험 절차
3-[(4-Acetyl-3-hydroxy-2-propylphenoxy)methyl]-2-ethoxybenzoic acid was allowed to react with 3-pyridine butanamine according to the procedure of Example 32 and the product was purified by recrystallization from methylene chloride-ether to give, 3-[(4-Acetyl-3-hydroxy-2-propylphenoxy-methyl]-2-ethoxy-[4-(3-pyridinyl)butyl]benzamide, the title compound, mp 107°-109° in 73% yield.
후처리
- custom