Methane → epsilon(4-Amino 2-methoxy-benzenesulfonamido)caproic acid

HRID 65271노트

반응식

HRID 65271 반응식
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10]([NH:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]([OH:21])=[O:20])(=[O:12])=[O:11])=[C:6]([O:22][CH3:23])[CH:5]=1)([O-])=O.C>C(OCC)(=O)C>[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([S:10]([NH:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]([OH:21])=[O:20])(=[O:11])=[O:12])=[C:6]([O:22][CH3:23])[CH:5]=1

참가 물질

4

반응물 2

HCID 297MethaneHCID 13192117epsilon(4-Nitro 2-methoxy-benzenesulfonamido)caproic acid

생성물 1

HCID 13192164epsilon(4-Amino 2-methoxy-benzenesulfonamido)caproic acid수율 98%

시약·촉매·용매 1

HCID 8857Ethyl Acetate용매

실험 절차

A solution of ε(4-nitro 2-methoxy-benzenesulfonamido)caproic acid (1.4 g) in solution in ethyl acetate (150 cm3) is stirred magnetically under a hydrogen atmosphere in the presence of 5% palladized charcoal (120 mg). After four hours, the hydrogen absorption being terminated, the catalyst is filtered and the filtrate concentrated under reduced pressure. Pure ε(4-amino 2-methoxy-benzenesulfonamido)caproic acid is obtained, with a yield of 98%.

후처리

  1. customthe hydrogen absorption
  2. custombeing terminated
  3. filtrationthe catalyst is filtered
  4. concentrationthe filtrate concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-0798acd525f64795904670e72a5587f5
출처 데이터셋
uspto-grants-1986_09
특허 번호
US04613618

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