Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,3-Dichloroanisole → 2,3-Dichloro-4-methoxy-4'-fluorobenzophenone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,3-Dichloroanisole | HCID 16126 | — |
| 반응물 | 4-Fluorobenzoyl chloride | HCID 67879 | — |
| 반응물 | Aluminum(III) Chloride | HCID 6451240 | — |
| 용매 | 1,2-Dichloroethane | HCID 11 | — |
| 생성물 | 2,3-Dichloro-4-methoxy-4'-fluorobenzophenone | HCID 20150631 | — |
반응 단계
The Friedel-Crafts procedure of Example 24a is repeated with 31.55 g of p-fluorobenzoyl chloride, 32 g of 2,3-dichloroanisole and 35.22 g of AlCl3 combined in 1,2-dichloroethane and reacted. The resultant crude product is triturated with warm hexane, cooled and filtered to yield 2,3-dichloro-4-methoxy-4'-fluorobenzophenone.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04673746 |
| 출처 데이터셋 | uspto-grants-1987_06 |
| ORD ID | ord-16d2b1f25727477b870fde75392c2ede |
| 출처 메모 | uspto-grants-1987_06 |