Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl Acetate → L-Phenylalanine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl Acetate | HCID 8857 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | DL-Phenylalanine, methyl ester | HCID 75737 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | L-Phenylalanine | HCID 6140 | 98% |
반응 단계
A mixture of 1.15 grams of D,L-phenylalanine methyl ester in 2.5 milliliters of water was added to 5.0 milliliters of ethyl acetate. The pH was adjusted to 6.5 with 2.5 milliliters of sodium hydroxide. Two milligrams of chymotrypsin was added and the reaction was stirred gently at room temperature. A white precipitate appeared after 1.5 hours. The precipitate was isolated after 2 hours yielding 0.22 grams with an optical rotation equivalent to 98% pure L-phenylalanine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04613691 |
| 출처 데이터셋 | uspto-grants-1986_09 |
| ORD ID | ord-a1998eaeb8504d398dcc88c0ffe4372b |
| 출처 메모 | uspto-grants-1986_09 |