Trifluoroacetic acid → HCID 131717450, 화합물

HRID 653858노트

반응식

HRID 653858 반응식
NC1SN=C(/[C:7](=N/OCF)/[C:8]([NH:10][C@@H:11]2[C:32](=[O:33])[N:13]3[C:14]([C:29]([O-:31])=[O:30])=[C:15](/[CH:18]=[CH:19]/[CH2:20][N+:21]([CH2:25][C:26](=[O:28])[NH2:27])([CH2:23]C)[CH3:22])[CH2:16][S:17][C@H:12]23)=[O:9])N=1.[F:38][C:39]([F:44])([F:43])[C:40]([OH:42])=[O:41].[C:45]1(OC)[CH:50]=[CH:49][CH:48]=[CH:47][CH:46]=1>>[F:38][C:39]([F:44])([F:43])[C:40]([O-:42])=[O:41].[C:45]1([CH2:7][C:8]([NH:10][C@@H:11]2[C:32](=[O:33])[N:13]3[C:14]([C:29]([OH:31])=[O:30])=[C:15](/[CH:18]=[CH:19]/[CH2:20][N+:21]([C@@H:25]([C:26](=[O:28])[NH2:27])[CH3:39])([CH3:22])[CH3:23])[CH2:16][S:17][C@H:12]23)=[O:9])[CH:46]=[CH:47][CH:48]=[CH:49][CH:50]=1

참가 물질

4

반응물 3

HCID 6422Trifluoroacetic acidHCID 7519AnisoleHCID 6536774Cefluprenam

생성물 1

HCID 131717450HCID 131717450, 화합물

실험 절차

In a similar manner as in Example 5, the compound (34.5 g) of Example 14 was suspended in anisole (210 ml), followed by an addition of trifluoroacetic acid (230 ml) to obtain the target compound (25.9 g).

출처 및 근거

ORD 기록
ord-b1b3598b01e04618bd12feda8544a772
출처 데이터셋
uspto-grants-1992_07
특허 번호
US05128465

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