Acetic Acid → 1,4-Bis[2-(2-hydroxypropylamino)ethylamino]-5,8-dihydroxyanthraquinone diacetate salt

HRID 65402노트

반응식

HRID 65402 반응식
[OH:1][CH:2]([CH3:34])[CH2:3][NH:4][CH2:5][CH2:6][NH:7][C:8]1[C:21]2[C:20](=[O:22])[C:19]3[C:14](=[C:15]([OH:24])[CH:16]=[CH:17][C:18]=3[OH:23])[C:13](=[O:25])[C:12]=2[C:11]([NH:26][CH2:27][CH2:28][NH:29][CH2:30][CH:31]([OH:33])[CH3:32])=[CH:10][CH:9]=1.[C:35]([OH:38])(=[O:37])[CH3:36].C(O)C>CC(C)=O>[C:35]([OH:38])(=[O:37])[CH3:36].[C:35]([OH:38])(=[O:37])[CH3:36].[OH:1][CH:2]([CH3:34])[CH2:3][NH:4][CH2:5][CH2:6][NH:7][C:8]1[C:21]2[C:20](=[O:22])[C:19]3[C:14](=[C:15]([OH:24])[CH:16]=[CH:17][C:18]=3[OH:23])[C:13](=[O:25])[C:12]=2[C:11]([NH:26][CH2:27][CH2:28][NH:29][CH2:30][CH:31]([OH:33])[CH3:32])=[CH:10][CH:9]=1

참가 물질

5

반응물 3

HCID 176Acetic AcidHCID 702EthanolHCID 4330601,4-Dihydroxy-5,8-bis[2-(2-hydroxypropylamino)ethylamino]anthracene-9,10-dione

생성물 1

HCID 867369171,4-Bis[2-(2-hydroxypropylamino)ethylamino]-5,8-dihydroxyanthraquinone diacetate salt

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

A mixture of 228 mg. of 1,4-bis[2-(2-hydroxypropylamino)ethylamino]-5,8-dihydroxyanthraquinone, 60 mg. of glacial acetic acid, and 10 ml. of ethanol is heated on a steam bath for 10 minutes, cooled, treated with 50 ml. of acetone and cooled to obtain the title compound.

후처리

  1. additionA mixture of 228 mg
  2. temperaturecooled
  3. additiontreated with 50 ml

출처 및 근거

ORD 기록
ord-b94e2c0a210a4f5293c43cae03a6d212
출처 데이터셋
uspto-grants-1986_09
특허 번호
US04614618

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