Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Aniline → 2-Hydroxy-N-phenyl-11H-benzo[A]carbazole-3-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Aniline | HCID 6115 | — |
| 반응물 | 1,2-Dichlorobenzene | HCID 7239 | — |
| 반응물 | Phosphorus oxychloride | HCID 24813 | — |
| 반응물 | 2-Hydroxy-11H-benzo[a]carbazole-3-carboxylic acid | HCID 66531 | — |
| 생성물 | 2-Hydroxy-N-phenyl-11H-benzo[A]carbazole-3-carboxamide | HCID 15596992 | — |
반응 단계
2-Hydroxy-11H-benzo(a)carbazole-3-carboxylic acid (0.5 gram, 1.8 millimoles) was reacted with aniline (0.44 gram, 4.5 millimoles) in 10 milliliters of o-dichlorobenzene in the presence of a condensing reagent, phosphorus oxychloride (0.37 gram, 2.4 millimoles), at reflux under a nitrogen atmosphere. After 5 hours, TLC analysis revealed that the starting acid was consumed, but that no anilide product, 2-hydroxy-11H-benzo(a)carbazole-3-carboxanilide, was formed.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05130443 |
| 출처 데이터셋 | uspto-grants-1992_07 |
| ORD ID | ord-14423a94ba964f5587f7db69a26a6ddf |
| 출처 메모 | uspto-grants-1992_07 |