Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Iodothiophene → (S)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(2-thienyl)ethynyl]-2H-1-benzopyran-6-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Iodothiophene | HCID 18921 | — |
| 반응물 | (S)-2-ethynyl-3,4-dihydro-2,5,7,8-tetramethyl-2H-1-benzopyran-6-ol | HCID 9859440 | — |
| 생성물 | (S)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(2-thienyl)ethynyl]-2H-1-benzopyran-6-ol | HCID 15171811 | — |
반응 단계
This enantiomer was obtained as described in Example 4 by reacting the (S)-3,4-dihydro-2-ethynyl-2,5,7,8-tetramethyl-2H-1-benzopyran-6-ol from Example 11 with 2-iodothiophene. It was isolated by chromatography as above and was crystallized from ether/hexane to yield colorless crystals with m.p. 131°-134° C. [α]D25 =+34.9° (c=1.145 in MeOH).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05132310 |
| 출처 데이터셋 | uspto-grants-1992_07 |
| ORD ID | ord-5f6430ca414548349bb241fd1e4f9443 |
| 출처 메모 | uspto-grants-1992_07 |