Methallyl alcohol → 2,4,5-Trifluoro-6-methallyloxyisopthalonitrile

HRID 65456

반응식

HRID 65456 반응식
F[C:2]1[C:7]([C:8]#[N:9])=[C:6]([F:10])[C:5]([C:11]#[N:12])=[C:4]([F:13])[C:3]=1[F:14].[CH3:15][C:16]([CH2:18][OH:19])=[CH2:17].[F-].[K+]>C(#N)C>[F:10][C:6]1[C:5]([C:11]#[N:12])=[C:4]([F:13])[C:3]([F:14])=[C:2]([O:19][CH2:18][C:16](=[CH2:15])[CH3:17])[C:7]=1[C:8]#[N:9]

참가 물질

5

반응물 3

HCID 10557Methallyl alcoholHCID 522689Potassium FluorideHCID 608182Tetrafluoroisophthalonitrile

생성물 1

HCID 137155472,4,5-Trifluoro-6-methallyloxyisopthalonitrile

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

The mixture of 3.0 g of tetrafluoroisophthalonitrile, 1.2 g of β-methallyl alcohol and 1.8 g of potassium fluoride in 30 ml of acetonitrile was stirred at room temperature for 10 hours. The mixture was cooled and filtered. The filtrate was evaporated under reduced pressure. After 50 ml of water was added to the residue, the mixture was extracted with carbon tetrachloride, washed with water, and dried over sodium sulfate. After evaporating carbon tetrachloride, the residue of 2.9 g (crystal) was obtained.

후처리

  1. temperatureThe mixture was cooled
  2. filtrationfiltered
  3. customThe filtrate was evaporated under reduced pressure
  4. additionAfter 50 ml of water was added to the residue
  5. extractionthe mixture was extracted with carbon tetrachloride
  6. washwashed with water
  7. dry with materialdried over sodium sulfate
  8. customAfter evaporating carbon tetrachloride
  9. customthe residue of 2.9 g (crystal) was obtained

출처 및 근거

ORD 기록
ord-7831062aa16349ff9fea5a3d81370c9c
출처 데이터셋
uspto-grants-1986_09
특허 번호
US04614742

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