Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Bromotrichloromethane → Ethyl 2-acetyl-2-bromobutyrate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Bromotrichloromethane | HCID 6383 | — |
| 반응물 | Butanoic acid, 2-ethyl-3-oxo-, ethyl ester | HCID 79065 | — |
| 반응물 | Tetrabutylammonium Fluoride Trihydrate | HCID 11726816 | — |
| 생성물 | Ethyl 2-acetyl-2-bromobutyrate | HCID 11009975 | 56.5% |
반응 단계
In a 10 mL round-bottom flask, 1.58 g of ethyl 2-acetylbutyrate (10 mmol), 2.1 g bromotrichloromethane (10.5 mmol), and 200 mg of tetra-n-butylammonium fluoride trihydrate (0.632 mmol) were mixed at 24° C. for 1 h. Gas chromatographic analysis of the resulting mixture showed the presence of 1.34 g of ethyl 2-acetyl-2-bromobutyrate (56% yield).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05132475 |
| 출처 데이터셋 | uspto-grants-1992_07 |
| ORD ID | ord-402593d179124bc695f6000a2107b035 |
| 출처 메모 | uspto-grants-1992_07 |