cis-2-BUTENE → HCID 15008616, 화합물

HRID 654858노트

반응식

HRID 654858 반응식
[CH3:1]/[CH:2]=[CH:3]\[CH3:4].[F:5][C:6]1[CH:11]=[CH:10][C:9]([C:12](=[O:19])[CH2:13][N:14]2[CH:18]=[N:17][CH:16]=[N:15]2)=[CH:8][CH:7]=1>>[F:5][C:6]1[CH:11]=[CH:10][C:9]([C@@:12]2([CH2:13][N:14]3[CH:18]=[N:17][CH:16]=[N:15]3)[CH:3]([CH3:4])[C@@H:2]([CH3:1])[O:19]2)=[CH:8][CH:7]=1

참가 물질

3

반응물 2

HCID 5287573cis-2-BUTENEHCID 104204761-(4-Fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone

생성물 1

HCID 15008616HCID 15008616, 화합물수율 5.3%

실험 절차

Following a procedure similar to that described in Example 39, but using cis-2-butene and 950 mg (5.68 mmole) of 4'-fluoro-2-(1H-1,2,4-triazol-1-yl)-acetophenone, 80 mg (yield 5.3%) of a 1:1 mixture of stereoisomers at the 3-position of the title compound were obtained, in the form of oil.

출처 및 근거

ORD 기록
ord-ef18e4f183ec4e7685e400a533941623
출처 데이터셋
uspto-grants-1992_07
특허 번호
US05134152

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