5-Phenyl-1-pentanol → Cyclohexanepentanol

HRID 654896노트

반응식

HRID 654896 반응식
[C:1]1([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][OH:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[H][H]>C(O)(=O)C.C(OCC)C.[Pt]=O>[CH:1]1([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][OH:12])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

참가 물질

6

반응물 2

HCID 615235-Phenyl-1-pentanolHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 269450Cyclohexanepentanol

시약·촉매·용매 3

HCID 82844Platinum oxide (PtO)촉매HCID 176Acetic Acid용매HCID 3283Diethyl Ether용매

실험 절차

To a solution of 5-phenylpentanol (2.21 g., 13.5 mmol) in ten ml glacial acetic acid was added amorphous platinum oxide (0.40 g., 1.76 mmol, oxygen activated). This mixture was subjected to three atm. of hydrogen with agitation (Parr hydrogenator) at room temperature for four hours. The reaction mixture was diluted with ethyl ether, filtered through celite, washed repeatedly with saturated sodium bicarbonate, followed by water and saturated sodium chloride solution. The organic portion was filtered, dried over magnesium sulfate, filtered and concentrated to give the desired alcohol.

후처리

  1. filtrationfiltered through celite
  2. washwashed repeatedly with saturated sodium bicarbonate
  3. filtrationThe organic portion was filtered
  4. dry with materialdried over magnesium sulfate
  5. filtrationfiltered
  6. concentrationconcentrated

출처 및 근거

ORD 기록
ord-2ecf8f125a674a57bc18840d689fdf3f
출처 데이터셋
uspto-grants-1992_07
특허 번호
US05134128

반응 노트

불러오는 중…