trans-3-(2-Pyridyl)cyclopentylamine → cis-3-(2-Pyridyl)cyclopentylamine

HRID 655146노트

반응식

HRID 655146 반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C@@H:7]1[CH2:11][CH2:10][C@H:9]([N:12]2C(=O)C3=CC=CC=C3C2=O)[CH2:8]1.N1C=CC=CC=1[C@H]1CC[C@H](N)C1>>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C@@H:7]1[CH2:11][CH2:10][C@H:9]([NH2:12])[CH2:8]1

참가 물질

3

반응물 2

HCID 59486146trans-3-(2-Pyridyl)cyclopentylamineHCID 67133552cis-N-[3-(2-pyridyl)cyclopentyl]phthalimide

생성물 1

HCID 67133525cis-3-(2-Pyridyl)cyclopentylamine수율 99%

실험 절차

The title compound (498 mg, 99%) was prepared from cis-N-[3-(2-pyridyl)cyclopentyl]phthalimide (905 mg, 3.10 mmol) in a manner similar to that described for the preparation of trans-3-(2-pyridyl)cyclopentylamine.

출처 및 근거

ORD 기록
ord-6df9eb44cde64698866d3a3224452bba
출처 데이터셋
uspto-grants-2011_12
특허 번호
US08071591B2

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