Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(1S,4S)-4-(3-pyridyl)-2-cyclopenten-1-ol → (1R,3R)-3-(3-pyridyl)cyclopentanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (1S,4S)-4-(3-pyridyl)-2-cyclopenten-1-ol | HCID 59486121 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | (1R,3R)-3-(3-pyridyl)cyclopentanol | HCID 59486143 | 97% |
반응 단계
A mixture of (1S,4S)-4-(3-pyridyl)-2-cyclopenten-1-ol (1.86 g, 11.5 mmol) and 10% Pd/C (186 mg) in EtOH (35 mL) was stirred under hydrogen atmosphere for 3 h. The catalyst was removed by filtration over Celite and the filtrate was concentrated in vacuo. (1R,3R)-3-(3-pyridyl)cyclopentanol (1.82 g, 97%) was yield as yellow oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08071591B2 |
| 출처 데이터셋 | uspto-grants-2011_12 |
| ORD ID | ord-f2d094fcfd834f89a25ee48b8793f655 |
| 출처 메모 | uspto-grants-2011_12 |