참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | Phenol | HCID 996 | — |
| 반응물 | Boric Acid | HCID 7628 | — |
| 반응물 | 1-Chlorohexadecane | HCID 20993 | — |
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | 9,10-Anthracenedione, 1-amino-4,5-dihydroxy-8-nitro- | HCID 5484079 | — |
| 반응물 | HCID 20233208 | HCID 20233208 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Toluene | HCID 1140 | — |
| 용매 | Nitrobenzene | HCID 7416 | — |
| 생성물 | HCID 20233207 | HCID 20233207 | — |
반응 단계
120 parts of phenol, 6.1 parts (0.1 mole) of boric acid and 70 parts of toluene are refluxed, while stirring, the water of reaction formed thereby being removed from the system. The toluene is then distilled off, the mixture is cooled to 110° C. and 25.4 parts (0.05 mole) of 1-palmitylamino-8-amino-4,5-dihydroxyanthraquinone (prepared by reacting 1-amino-8-nitro-4,5-dihydroxyanthraquinone with palmityl chloride in nitrobenzene and then reducing the product with hydrazine hydrate) are added. Ammonia is then passed in at this temperature until no further starting material can be detected in the thin-layer chromatogram (duration: 3 hours). The reaction mixture is cooled to 90° C. and 240 parts of methanol are added. After cooling to room temperature, the dye precipitated is filtered off with suction and the material on the filter is washed with methanol and water and dried. 20 parts of 1,4-diamino-5-hydroxy-8-palmitylaminoanthraquinone of melting point 174° C. are obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04614804 |
|---|
| 출처 데이터셋 | uspto-grants-1986_09 |
|---|
| ORD ID | ord-e81c7b4ace6c436c8bde44d85e7a56a3 |
|---|
| 출처 메모 | uspto-grants-1986_09 |
|---|
