Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenethyl Isothiocyanate → 1-(1-methyl-1H-pyrrol-2-ylmethyl)-3-phenethylthiourea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenethyl Isothiocyanate | HCID 16741 | — |
| 반응물 | (1-methyl-1H-pyrrol-2-yl)methanamine | HCID 2776207 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 1-(1-methyl-1H-pyrrol-2-ylmethyl)-3-phenethylthiourea | HCID 59088007 | 60.1% |
반응 단계
(1-methyl-1H-pyrrol-2-yl)methylamine (65 mg) and (2-isothiocyanatoethyl)benzene (100 mg) were dissolved in ethyl acetate (20 ml) and the solution was stirred for 12 hours. After the completion of the reaction, the resulting mixture was purified by column-chromatography (ethyl acetate/hexane=1/3) to yield the compound 17-3 (97 mg, 60%) as a brown liquid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08071650B2 |
| 출처 데이터셋 | uspto-grants-2011_12 |
| ORD ID | ord-60190a4c30bd418ea67d301a066e7155 |
| 출처 메모 | uspto-grants-2011_12 |