(3-Benzyloxy-5-trifluoromethyl-phenyl)-acetic acid ethyl ester → (3-Hydroxy-5-trifluoromethyl-phenyl)-acetic acid ethyl ester

참여 물질

반응 조건

반응 단계

(3-Benzyloxy-5-trifluoromethyl-phenyl)-acetic acid ethyl ester (1.7 g, 5.6 mmol) was dissolved in EtOH (30 mL) and degassed with N2. 5% Palladium on carbon (1 g) was added, and the reaction was purged with H2 and then stirred under an H2 balloon at 50° C. overnight. The mixture was filtered and concentrated to give (3-Hydroxy-5-trifluoromethyl-phenyl)-acetic acid ethyl ester.

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