2,3-Dichloroaniline → 4-Chloro-5-fluoro-2-indanamine

반응식

[Cl:1][C:2]1[C:8]([F:9])=[CH:7][CH:6]=[CH:5][C:3]=1N.Cl[C:11]1C(Cl)=CC=[CH:14][C:12]=1[NH2:13]>>[Cl:1][C:2]1[C:8]([F:9])=[CH:7][CH:6]=[C:5]2[C:3]=1[CH2:11][CH:12]([NH2:13])[CH2:14]2

참가 물질

반응물 2

HCID 118442,3-Dichloroaniline

HCID 888842-Chloro-3-fluoroaniline

생성물 1

HCID 227576964-Chloro-5-fluoro-2-indanamine

실험 절차

Substituting 2-chloro-3-fluoroaniline as a starting material for 2,3-dichloroaniline and following the procedure of Example 1 yields 4-chloro-5-fluoro-2-indanamine.

출처 및 근거

ORD 기록: ord-ce8da3ae08d84b42a8239e12205332b7
출처 데이터셋: uspto-grants-1978_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04128666

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