Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Iodoethane → N-Ethylphenothiazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Iodoethane | HCID 6340 | — |
| 반응물 | Phenothiazine | HCID 7108 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 촉매 | Tetrabutylammonium hydrogen sulfate | HCID 94433 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | N-Ethylphenothiazine | HCID 219178 | — |
반응 단계
A mixture of 10 g (0.05 mol) of phenothiazine, 11.7 g (0.075 mol) of iodoethane, 4.2 g (0.075 mol) of potassium hydroxide and 0.25 g of tetra-n-butylammonium hydrogen sulfate in 200 ml of dry toluene was refluxed for 24 hours. After cooling, the reaction mixture was filtered, and the solvent was evaporated. The product was crystallized from methanol. The yield of 10-ethylphenothiazine (C14H13NS, FW=227.33) was 90%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07083884B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-625c6e1d30dd4d0a9f0e4279bcd0f5ff |
| 출처 메모 | uspto-grants-2006_08 |