1,1-Dimethylhydrazine → alpha-Dimethylhydrazinocarbonylamino-2-thiopheneacetic acid
반응식
[N:1]([CH:4]([C:10]1[S:11][CH:12]=[CH:13][CH:14]=1)[C:5]([O:7]CC)=[O:6])=[C:2]=[O:3].[CH3:15][N:16]([CH3:18])[NH2:17].C(Cl)Cl>C(O)(=O)C>[CH3:15][N:16]([CH3:18])[NH:17][C:2]([NH:1][CH:4]([C:10]1[S:11][CH:12]=[CH:13][CH:14]=1)[C:5]([OH:7])=[O:6])=[O:3]참가 물질
5
실험 절차
A solution of 4.2 g. (0.02 mole) of DL-α-isocyanato-2-thiopheneacetic acid, ethyl ester and 1.2 g. (0.02 mole) of N,N-dimethylhydrazine in 80 ml. of methylene chloride is stirred overnight. The solution is concentrated and to the syrupy residue are added 10 ml. of 2N sodium hydroxide solution. After stirring for 30 minutes, a clear yellow solution results. By the addition of acetic acid, 3.9 g. of α-dimethylhydrazinocarbonylamino-2-thiopheneacetic acid are obtained, m.p. 208°-210°.
후처리
- concentrationThe solution is concentrated and to the syrupy residue
- additionare added 10 ml
- customa clear yellow solution results
출처 및 근거
- ORD 기록
- ord-208d1fa98d07437e8ee5455d106b3405
- 출처 데이터셋
- uspto-grants-1978_12
- 특허 번호
- US04128724
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