4-Amino-3-fluorophenol → HCID 19986948, 화합물

반응식

[Cl:1][C:2]1[CH:7]=[C:6]([N+:8]([O-])=O)[CH:5]=[C:4]([F:11])[C:3]=1[OH:12].NC1C=CC(O)=CC=1F>>[NH2:8][C:6]1[CH:5]=[C:4]([F:11])[C:3]([OH:12])=[C:2]([Cl:1])[CH:7]=1

참가 물질

반응물 2

HCID 27359194-Amino-3-fluorophenol

HCID 59987459757251-37-9

생성물 1

HCID 19986948HCID 19986948, 화합물수율 40%

실험 절차

This compound was prepared from 2-chloro-6-fluoro-4-nitrophenol (1.3 g, 6.79 mmol) in the manner described for 4-amino-3-fluorophenol, affording 0.34 g (40%) of 4-amino-2-chloro-6-fluorophenol. 1H-NMR (DMSO-d6) δ 4.99 (s, 2H), 6.29-6.36 (m, 2H), 8.85 (s, 1H).

출처 및 근거

ORD 기록: ord-8591feb903e143d8a637d775e505f94b
출처 데이터셋: uspto-grants-2011_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08076488B2

반응 노트

불러오는 중…