3-Pyridinecarboxaldehyde → Ethyl 2-methyl-2-(pyridin-3-ylmethylamino)propanoate

HRID 658797

반응식

[CH:1](=O)[C:2]1[CH:7]=[CH:6][CH:5]=[N:4][CH:3]=1.Cl.[NH2:10][C:11]1([C:14]([O:16][CH2:17][CH3:18])=[O:15])[CH2:13][CH2:12]1>>[CH3:12][C:11]([NH:10][CH2:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][CH:7]=1)([CH3:13])[C:14]([O:16][CH2:17][CH3:18])=[O:15]

참가 물질

반응물 2

HCID 103713-Pyridinecarboxaldehyde

HCID 386203Ethyl 1-aminocyclopropane-1-carboxylate hydrochloride

생성물 1

HCID 59524391Ethyl 2-methyl-2-(pyridin-3-ylmethylamino)propanoate수율 95%

실험 절차

Prepared as in Example 12-1b from nicotinaldehyde and ethyl 1-aminocyclopropanecarboxylate hydrochloride. Yield 95%, a white solid. MS 223 (MH+).

출처 및 근거

ORD 기록: ord-faa42982028645818b84c034bb81c130
출처 데이터셋: uspto-grants-2011_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08076491B2

연결된 노트

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