1,2-Diaminocyclohexane, cis- → cis-N-(2-Amino-cyclohexyl)-2-cyclopropyl-4-trifluoromethyl-benzamide

HRID 659191

반응식

HRID 659191 반응식
[NH2:1][C@@H:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C@@H:3]1[NH2:8].[CH:9]1([C:12]2[CH:20]=[C:19]([C:21]([F:24])([F:23])[F:22])[CH:18]=[CH:17][C:13]=2[C:14](O)=[O:15])[CH2:11][CH2:10]1>>[NH2:1][C@H:2]1[CH2:7][CH2:6][CH2:5][CH2:4][C@H:3]1[NH:8][C:14](=[O:15])[C:13]1[CH:17]=[CH:18][C:19]([C:21]([F:22])([F:23])[F:24])=[CH:20][C:12]=1[CH:9]1[CH2:10][CH2:11]1

참가 물질

3

반응물 2

HCID 3429171,2-Diaminocyclohexane, cis-HCID 594384852-Cyclopropyl-4-(trifluoromethyl)benzoic acid2회

생성물 1

HCID 66681224cis-N-(2-Amino-cyclohexyl)-2-cyclopropyl-4-trifluoromethyl-benzamide

실험 절차

The title compound, yellow solid, MS: m/e=327.2 [(M+H)+], was prepared in accordance with the general method of intermediate G from cis-1,2-diaminocyclohexane and 2-cyclopropyl-4-trifluoromethyl-benzoic acid (intermediate K).

출처 및 근거

ORD 기록
ord-b9fc94ab694347f3bf2137dcf8d887dd
출처 데이터셋
uspto-grants-2011_12
특허 번호
US08080541B2

연결된 노트

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